Product Name :
Phospho-CrkL (Y207) Recombinant Rabbit Monoclonal Antibody [JE55-58]
Predicted band size :
34 kDa
Observed band size :
38 kDa
Synonyms:
Crk L antibody Crk like protein antibody Crk-like protein antibody Crkl antibody CRKL_HUMAN antibody Crkol antibody HGNC:2363 antibody Oncogene CrkL antibody V crk avian sarcoma virus CT10 oncogene homolog like antibody v crk sarcoma virus CT10 oncogene homolog (avian) like antibody 展开
Function :
Crk-like protein is a protein that in humans is encoded by the CRKL gene. v-CRK avian sarcoma virus CT10-homolog-like contains one SH2 domain and two SH3 domains. CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential. CrkL together with Crk participates in the Reelin signaling cascade downstream of DAB1.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic phosphopeptide corresponding to residues surrounding Tyr207 of human CrkL protein.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
JE55-58
RRID:
AB_3072788
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.5-Bromo-1,3-dihydroisobenzofuran manufacturer Aliquot store at -20℃.Monomethyl auristatin E Chemscene Avoid repeated freeze / thaw cycles.PMID:33622227
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 34 kDa
Positive control :
K-562 cell lysate.