Product Name :
OAZ3 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Ornithine decarboxylase antizyme 3 OAZ3 antibody
Function :
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 3, the third member of the antizyme family. Like antizymes 1 and 2, antizyme 3 inhibits ODC activity and polyamine uptake; however, it does not stimulate ODC degradation. Also, while antizymes 1 and 2 have broad tissue distribution, expression of antizyme 3 is restricted to haploid germ cells in testis, suggesting a distinct role for this antizyme in spermiogenesis. Antizyme 3 gene knockout studies showed that ho
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from human protein . at AA range: 90-170
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.tert-Butyl (3-iodopropyl)carbamate Price Aliquot store at -20℃ or -80℃.1239591-03-7 Chemscene Avoid repeated freeze / thaw cycles.PMID:33394079
Storage buffer solution:
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
20 kDa
Positive control :
Breast,